Join Our Clinical Study + Complimentary Product - [Shop](/content/collections/shop-products/index.html) - [Providers](/content/pages/hcp-homepage/index.html) - [Science](/content/pages/technology/index.html) - [Reviews](/content/pages/reviews/index.html) - Cart - 0 - Account [Skip to content](/content/pages/technology#MainContent/index.html) The Science Behind Phage-Based Acne Care ## What Are Bacteriophages? Phyla uses 'phages'—naturally occurring microorganisms that selectively target C. acnes, the bacteria associated with acne. By focusing only on acne-causing bacteria, phages support a balanced skin microbiome. [Explore the System](/content/products/acne-phage-system/index.html) ### Phyla Dermatology & Clinical Advisory Board ### Dr. Lisa Akintilo, M.D NYU Langone Health ### Cynthia Trickett, MPAS, PA-C North Dallas Dermatology Associates ### Dr. Hilary Baldwin, M.D. Acne Treatment & Research Center ### Dr. Julie Harper, MD Dermatology and Skin Care Center of Birmingham ## Acne and the Skin Microbiome ## Acne and the Skin Microbiome Healthy skin depends on a balanced microbiome—a community of beneficial bacteria that protects the skin barrier. When C. acnes bacteria become dominant, inflammation and breakouts can occur. Unlike traditional treatments that disrupt bacteria broadly, bacteriophages selectively target C. acnes while leaving beneficial bacteria intact. [Start Clearing](/content/products/acne-phage-system/index.html) ## Dermatologist-recommended for a reason 0 Reduction in C. acnes 0 Reported side effects inclinical trials 0 Reported healthier-lookingskin by week 4 0 Patented phage technology ## Phyla vs. Traditional Treatments ### Traditional Treatments Many acne treatments eliminate bacteria broadly, which can disrupt the skin barrier and microbiome. ### Phage Technology Bacteriophages are naturally occurring microorganisms that selectively target C. acnes, leaving beneficial bacteria intact. Phyla’s serum contains billions of bacteriophages that activate on contact with the skin. These phages selectively infect C. acnes, helping reduce acne while preserving beneficial microbes. ### Hormonal Acne Linked to fluctuations in hormones particularly during puberty, menstruation, pregnancy, or menopause. **Phyla’s Approach:** Helps regulate the inflammatory response triggered by hormonal changes. ### Cystic Acne A more severe form of acne caused characterized by large, painful, pus-filled, bumps deep beneath the skin. **Phyla’s Approach:** Targets the bacteria associated with deep, inflamed breakouts to help calm skin. ### Teen Acne Very common during puberty and is driven by hormonal changes that increase sebum production. **Phyla’s Approach:** A gentle, microbiome-friendly approach that avoids irritating treatments that are harsh on young skin. ### Nodular Acne Consists of hard, painful bumps beneath the skins surface. Often inflamed and can persist for weeks or months. **Phyla’s Approach:** Targets the bacteria associated with deep, inflamed breakouts to help calm skin. ### Blackheads Open comedones appearing as small, dark spots on the skin’s surface. The color is from oxidized sebum, not dirt. **Phyla’s Approach:** A balanced microbiome supports healthier pores and helps reduce clogging. ### Whiteheads Closed comedones that occur when pores are clogged with sebum or dead skin cells. **Phyla’s Approach:** A balanced microbiome supports healthier pores and helps reduce clogging. ### Hormonal Acne Linked to fluctuations in hormones particularly during puberty, menstruation, pregnancy, or menopause. **Phyla’s Approach:** Helps regulate the inflammatory response triggered by hormonal changes. ### Cystic Acne A more severe form of acne caused characterized by large, painful, pus-filled, bumps deep beneath the skin. **Phyla’s Approach:** Targets the bacteria associated with deep, inflamed breakouts to help calm skin. RESULTS FROM AN 8-WEEK CLINICAL STUDY ## **Clinical Research** 90 PATIENTS \| AGES 12–35 \| DOUBLE-BLIND PLACEBO CONTROLLED 90% Up to 90% reduction in _C. acnes_ bacteria vs placebo ### >70% saw reduction of lesions as early as 4–8 weeks ### 100% saw no side effects ### 93% reported healthier-looking skin by 4 weeks ## Phage Technology in Skincare Phyla's patented serum applies bacteriophage technology directly to the skin, offering a microbiome-focused approach to acne care. [Explore the System Details](/content/products/acne-phage-system/index.html) © 2025 PHYLA. ALL RIGHTS RESERVED. Contact Us: [info@phitherapeutics.com](mailto:info@phitherapeutics.com) [PRIVACY](/content/pages/privacy-policy-1/index.html) / [TERMS](/content/pages/terms/index.html) shop.app # shop.app is blocked This page has been blocked by an extension - Try disabling your extensions. ERR\_BLOCKED\_BY\_CLIENT Reload This page has been blocked by an extension phyla.com # phyla.com is blocked This page has been blocked by an extension - Try disabling your extensions. ERR\_BLOCKED\_BY\_CLIENT Reload This page has been blocked by an extension phyla.com # phyla.com is blocked This page has been blocked by an extension - Try disabling your extensions. ERR\_BLOCKED\_BY\_CLIENT Reload This page has been blocked by an extension phyla.com # phyla.com is blocked This page has been blocked by an extension - Try disabling your extensions. ERR\_BLOCKED\_BY\_CLIENT Reload This page has been blocked by an extension phyla.com # phyla.com is blocked This page has been blocked by an extension - Try disabling your extensions. ERR\_BLOCKED\_BY\_CLIENT Reload This page has been blocked by an extension phyla.com # phyla.com is blocked This page has been blocked by an extension - Try disabling your extensions. ERR\_BLOCKED\_BY\_CLIENT Reload This page has been blocked by an extension Your cart is empty.