Phyla Acne Phage Serum | Targeted Support for Breakout-Prone Skin – Phyla Skincare

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(519 reviewes)

The First and only Acne Phage Serum

Targets acne at the source. Preserves your skin

Tested + trusted by Derms

$ 60-day money back guarantee

Targets acne-causing bacteria at the source
Formulated with live bacteriophages What are bacteriophages?
Preserves your skin barrier and microbiome
Clinically tested on acne-prone skin
Gentle, non-irritating formula for daily use

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Trusted by Dermatologists Nationwide

“Patients love it — safe even for pregnant acne patients.”

- Dr. Lisa Akintilo, M.D Board Certified Dermatology

NYU Center

“Patients who struggled to achieve consistent clarity with other products reported significant improvement within just one month of using Phyla.”

- Jennfer Francis, PA-C

Ava MD

“You have the technology that can finally get rid of acne for everyone, and the derm community would forever be grateful.”

- Dr. Hillary Baldwin, M.D. Board-Certified Dermatologist

Acne Treatment & Research Center

“Your brand identified an unmet need in the market; targeting c. Acnes pathogenic strains while supporting the beneficial ones. This is remarkable.”

-Jamie Restivo, PA-C

CP Derm

“Phyla’s microbiome-focused approach is compelling, and the products are well tolerated and gentle on the skin”

- Dr. Bertha Baum, M.D. Board Certified Dermatologist

Aventura Dermatology

Earn up to 70 points \ \ Get 1 point for every $1 spent Sign up

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How It Works

Phages are naturally occurring microorganisms that selectively target C. acnes, the bacteria that drives acne.

Unlike traditional treatments that disrupt the skin, Phyla targets acne at the source while preserving your microbiome.

Ingredients

Key Ingredient: Phages

Live probiotic phages that selectively kill acne-causing bacteria while preserving the beneficial bacteria in your skin microbiome.

Full Ingredient List:

Water, Glycerin, Butylene Glycol, Hydroxyethylcellulose, C. Acnes Bacteriophage, Sodium Phosphate, Sodium Chloride, Phenoxyethanol, Polydextrose, Sclerotium Gum, Niacinamide, Magnesium Sulfate, Caffeine, Calcium Chloride, 0.5% Encapsulated Salicylic Acid

Proven in Clinics. Visible at Home.

Photos from everyday users. No filters, no post-processing.

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The System

Acne Phage System

Gel Cleanser

Anti-Blemish Moisturizer

Hormonal Acne

Linked to fluctuations in hormones particularly during puberty, menstruation, pregnancy, or menopause.

Phyla’s Approach: Helps regulate the inflammatory response triggered by hormonal changes.

Cystic Acne

A more severe form of acne caused characterized by large, painful, pus-filled, bumps deep beneath the skin.

Phyla’s Approach: Targets the bacteria associated with deep, inflamed breakouts to help calm skin.

Teen Acne

Very common during puberty and is driven by hormonal changes that increase sebum production.

Phyla’s Approach: A gentle, microbiome-friendly approach that avoids irritating treatments that are harsh on young skin.

Nodular Acne

Consists of hard, painful bumps beneath the skins surface. Often inflamed and can persist for weeks or months.

Phyla’s Approach: Targets the bacteria associated with deep, inflamed breakouts to help calm skin.

Blackheads

Open comedones appearing as small, dark spots on the skin’s surface. The color is from oxidized sebum, not dirt.

Phyla’s Approach: A balanced microbiome supports healthier pores and helps reduce clogging.

Whiteheads

Closed comedones that occur when pores are clogged with sebum or dead skin cells.

Phyla’s Approach: A balanced microbiome supports healthier pores and helps reduce clogging.

Hormonal Acne

Linked to fluctuations in hormones particularly during puberty, menstruation, pregnancy, or menopause.

Phyla’s Approach: Helps regulate the inflammatory response triggered by hormonal changes.

Cystic Acne

A more severe form of acne caused characterized by large, painful, pus-filled, bumps deep beneath the skin.

Phyla’s Approach: Targets the bacteria associated with deep, inflamed breakouts to help calm skin.

Acne Phage Serum

Add to cart - $70

$59

Treating Your Acne At The Source

No redness, dryness, peeling, or sensitivity.

4.53

Based on 519 reviews

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89% rated this product 4-5 stars

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Your questions, our solutions.

How long will it take to see results?

While some customers experience relief quickly, we recommend incorporating Phyla into your long-term skincare routine for the best results. True skin transformation happens at the cellular level, which typically becomes visible after 1-3 months of consistent use. Skin cells have a natural turnover cycle of about 28 days, and two months allow for multiple cycles, giving Phyla’s active ingredients time to penetrate deeply and work effectively. Acne is a persistent condition, and seeing real change takes patience. For optimal results, use the Phyla system twice daily to support a balanced microbiome and reduce the risk of future breakouts.

I have severe acne. What can I expect within the first few weeks?

If you have chronic or severe acne, your microbiome may take a bit longer to rebalance. In these cases, we advise using the full Acne Phage System consistently, twice daily, for at least two months. It’s possible that your acne may temporarily worsen as your skin adjusts, but rest assured Phyla won’t cause the dryness, redness, or irritation often seen with traditional acne treatments.

Can I use other products alongside Phyla?

We understand that skincare is a personal journey, and it’s natural to want to stick with products that work for you. To get the best results with Phyla, however, we suggest using the system exclusively. This reduces ingredient overload on your skin and allows our phages to work more effectively, helping to rebalance your microbiome and keep breakouts in check.

Are Phyla's products vegan and cruelty-free?

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A Lapse in Phyla Could Set You Back.

Missing even a day of Phyla can set back your progress and let acne-causing bacteria resurface. Subscribe to never run out and maintain long-term results.

Using Phyla daily is critical to see results
Any gap in usage can undo your progress
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